Eric Topol

Eric Topol


physician-scientist, author, editor. My new book is #DeepMedicine https://t.co/qin1EM5r23

338257 followers  •  499 follow  •    •   https://t.co/fYzaAmKQ2A

More on this by @katie_thomas  The FDA gave Gilead a priority review voucher worth $100 million w/ @peterbachmd  @akesselheim 

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My friend @alanalda  has a few words on voting for science, breaking his silence @AldaCenter  @PostOpinions 

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The experiment that did not require replication even got triplication. Now a runaway. One per second.

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In a (likely 1st) prospective study of 104 grocery store workers, 20% tested covid positive and 76% were asymptomatic @HarvardChanSPH 

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The tragic thing is when you know this will be the same headline for many weeks to come. And that it's preventable by @LaurenLeatherby 

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Belgium, worst country in the world for cases per capita in the 1st wave, has a repeat. New pandemic peak >1200/M

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It's the post fusion configuration of the #SARSCoV2  trimeric spike protein that blocks exposure of its receptor binding domain (RBD), like a Trojan horse, providing some of its defense against our immune response. Structural biology, cryo-EM insights.

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and 2nd in rising deaths to Czech Republic These two are very steep increases, extremely worrisome, with a fatality rate that has declined over the course the pandemic

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The science of #SARSCoV2  superspreading. Outstanding, just published @sciencemagazine  by and @martinenserink  @kakape 

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The patient had a whopping (8g) dose of a #SARSCoV2  neutralizing IgG antibody cocktail. Then they detected antibodies. You must be kidding me, Dr. Conley?

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We haven't see positive testing rates like this at any point during the US pandemic. Overall US positive test rate has shot up to 7.3%, and testing has decreased. South Dakota 43.4% Idaho 34.8% Wyoming 31.5% Wisconsin 28.0% Iowa 26.4% Alabama 25.2% Nebraska 21.8% Kansas 20.7%

Just published @TheLancet  The largest study of hydroxychloroquine shows a significant increase in death (~35%) and >2-fold increase of serious heart arrhythmias. ~96,000 patients, ~15,000 on HCQ or CQ from 671 hospitals, 6 continents.

How can a country that has required you to take your shoes off at airport security for a 2001 foiled attempt without a single person hurt ...... be the same one that has no systematic plan to address >73,000 Americans dead, >1.2 million confirmed cases?

The pandemic only lasted 103 in New Zealand and it has now gone 100 days since without a single new case. This paragraph is the key. Science-based Empathic leadership United Public Confidence Adherence to burdensome-control measures

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Covid reinfection in a 25 year-old man in Nevada, as confirmed by virus genomic sequencing; 2nd infection more severe @TheLancetInfDis 

What will go down as the biggest breakdown in the US response to #COVID19  is the lack of test kits. South Korea and the US had their 1st patients on Jan 20 and Jan 21, respectively. Look at the difference in daily testing. By March 4th, SK was ~18,000 per day.

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