Eric Topol

Eric Topol


physician-scientist, author, editor http://drerictopol.com

645449 followers  •  542 follow  •    •   http://www.scripps.edu/translational

Towards making not dying from Covid possible @OurWorldInData 

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"BA.4 and BA.2.12.1 can overcome immunity provided by earlier infections with other Omicron subvariants. " "This was unexpected...maybe we should adapt the system of naming " @houzhou — by @Nature  @amymaxmen 

The @CDCgov  changes its 2nd booster tune from "option" to "urge" for people age 50+ by “a steep and substan @SharonLNYTial  increase in hospitalizations for older Americans

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A small prospective #LongCovid  study cohort assessing persistent virus, autoimmunity, or immune activation failed to show any of these features were present or differed from controls @AnnalsofIM 

“Importantly, they found no differences in the levels of immunologic markers that might indicate a potential immunologic mechanism for PASC.” From accompanying editorial. Reminder: absence of evidence is not evidence of absence

Many previous #LongCovid  studies have documented auto-antibodies and persistent virus via biopsy. I don't only post studies that people like, but rather those in high quality journals likely to receive attention. The editorialist framed the deficiencies of this paper well 👇

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—BA.2 more symptoms than BA.1 —BA.2.12.1 and BA.4/5 more replication in lung cells than BA.2 —BA.4/5 more pathogenic than BA.2 in exp'tl model —BA.4/5 more immune escape than BA.2.12.1

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Ivermectin: the largest randomized, double-blind trial yet conducted, with early treatment, indicates there is no difference compared with placebo. It doesn't work. Period. just published @NEJM 

Almost the whole country is in the "Uncontrolled Spread" category 1/

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Airborne it is. 🦠 The 10 streams of overwhelming evidence by a 5-★ succi @TheLancetct  @trishgreenhalghu @kprather88 @Rschooleym @zeynep @jljcolorador @DFismany

The patient had a whopping (8g) dose of a #SARSCoV2  neutralizing IgG antibody cocktail. Then they detected antibodies. You must be kidding me, Dr. Conley?

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What happens when one of the best vaccinated (90% total population) countries in the world gets Omicron? PT

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Just published @Nature  The impact of #Covid  on the brain: the 1st longitudinal imaging study before and after infection, with controls Reduction of grey matter, brain size, cognitive decline

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Today, Canada surpassed Israel for fully vaccinated, a very high bar. Congratulations CA

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