Eric Topol

Eric Topol


physician-scientist, author, editor. My new book is #DeepMedicine https://t.co/qin1EM5r23

428545 followers  •  529 follow  •    •   https://t.co/fYzaAmKQ2A

Graphic from @trvrb  shows the transmissibility issue playing out in multiple countries outside of India, even though at ~1% level, except UK ~10% frequency. Whereas B.1.351 (SA) (most immune evasion of the variants) shows no sign of competing.

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Added 1.5 million US vaccinations (reported) today. If we keep up our current average of 800,000 1st dose vaccinees per day, we will reach 60% of population in <1 month

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2 more new reports to reassure about low incidence of myocarditis with covid 137 athletes screened 74 seropositive mild @CircAHA  cases with MRI assessment (w/controls) @JACCJournals 

One of the first studies to assess real-world effectiveness of the J&J 1-dose vaccine, matches Phase 3 clinical trial, at 77% HS preprint @MayoClinic  @MayoClinicHS 

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The dreaded cerebral venous thrombosis (CVST) occurs ~4/100,000 people with covid, many-fold higher than has been reported with vaccines (the type with thrombocytopenia, aka VITT)

The indirect, adverse impact of the pandemic on the diagnosis and monitoring of Type 2 #diabetes  @TheLancetEndo 

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Covid vaccination should be mandatory for healthcare workers. A "mildly coercive, conditional" vaccination policy involving temporary redeployment and eventual suspension laid out here

Who are these (un)masked men and women super spreaders? There are no clearcut genetic or demographic features of the people, or genomics of the virus, correlated with the people who over-disperse @TrendsMicrobiol 

Mortality reduction in the 5 states with the highest vaccination rates (most striking for Massachusetts which got down to zero yesterday)

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Airborne it is. 🦠 The 10 streams of overwhelming evidence by a 5-★ succi @TheLancetct  @trishgreenhalghu @kprather88 @Rschooleym @zeynep @jljcolorador @DFismany

Almost the whole country is in the "Uncontrolled Spread" category 1/

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This will go down in history as one of science and medical research's greatest achievements. Perhaps the most impressive. I put together a preliminary timeline of some key milestones to show how several years of work were compressed into months.

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One per thousand Americans have now died from covid-19. How does that compare with 12 other select countries with >20 million population?

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The patient had a whopping (8g) dose of a #SARSCoV2  neutralizing IgG antibody cocktail. Then they detected antibodies. You must be kidding me, Dr. Conley?

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Vaccines don't just work. They work across all the variants, providing protection from illness, hospitalizations, and deaths. Summary including today's multiple updates. (and we're damn lucky)

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You don’t get 3+ million shots a day without tens of thousands of volunteers. A salute to them. A sign of unity for a common, vital purpose

"The evidence is now clear. #SARSCoV2  is transmitted predominantly through the air — by people talking and breathing out large droplets and small particles called aerosols. Catching the virus from surfaces — although plausible — seems to be rare." @nature 

Just published @TheLancet  The largest study of hydroxychloroquine shows a significant increase in death (~35%) and >2-fold increase of serious heart arrhythmias. ~96,000 patients, ~15,000 on HCQ or CQ from 671 hospitals, 6 continents.

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