Meg Tirrell

Meg Tirrell


Biotech and pharma reporter for @CNBC

87530 followers  •  3332 follow  •    •   https://t.co/OPub4UDJuD

The latest in the annals of drug company execs explaining the vaccine manufacturing process to the world- J&J’s Dr Paul Stoffels: “You can't accelerate it by yelling at it.”

White House#covid19  briefing: @CDCDirector  says she remains “deeply concerned about a potential shift in the trajectory of the pandemic,” that recent declines “appear to be stalling at over 70K cases.” Says she’s “really worried” about states rolling back public health measures

@CDCDirector  . on J& #covid19J  vaccine: single-dose, easier to store and transport, which could make it suitable for clinics, mass vaccination sites that don’t have freezer capacity

Per CDC’s ACIP posted slides, the committee will discuss spacing out mRNA #covid19  vaccine doses today, as well as whether people who’ve had prior infection should receive just a single dose (spoiler alert: they don’t seem into either idea):

@JeffZients : J&J doses will be delivered as early as tomorrow. Allocating vaccine exact same way as Pfizer & Moderna, by population.

3.9M doses going out this week "is the entirety " of J&J's current inventory, @JeffZients  says. "Supply will be limited for the next couple of weeks... the co then expects to deliver approximately 16M additional doses by the end of March. " Predominantly in back half of month.

@JeffZients  .: Current 7-day avg o #covid19f  vaccinations in the US: 1.7M shots per day. Understates the current pace bc of storm impacts. Weekend saw new records of daily vaccinations.

@Laurie_Garrett  . asks at WH briefing about NY variant. Dr Fauci: "We are certainly taking the NY variant, 526, very seriously. " It started off in what is likely Washington Heights and then has gone through multiple boroughs.

Fauci on NY variant: Work done by David Ho has shown that we have to really keep an eye on it for its ability to evade both monoclonal antibodies and to a certain extent the vaccine-induced antibodies. (cc @apoorva_nyc  )

In clinical considerations for #covid19  vaccines, ACIP to say no product pref among the 3; the vaccines are *not* interchangeable; and says if a first dose of mRNA vaccine was received but the person can’t get another mRNA vaccine, they may get J&J:

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Dr Fauci: "There is a fact that permeates virology, and that is: Viruses cannot mutate if they don't replicate." Put it on a👕

Quest Diagnostics says its average turnaround time for #COVID19  tests is now 7 or more days for non priority 1 patients

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Pfizer puts out statement in response to numerous states saying they’ve been told their allotments of #covid19  vaccine have been reduced, & as FL cited Pfizer production issues as reason - noting no issues and millions of doses in warehouse they haven’t received instructions for.

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Regeneron notes of report President Trump has antibodies: “Given the volume of IgG antibodies delivered in our therapy, and the timing of these tests, it is likely that the second test is detecting REGN-COV2 antibodies.”

Weill Cornell’s Dr Matt McCarthy: “At one of the busiest hospitals in the country, I don’t have (a test) at my fingertips. I still have to call the Dept of Health, make my case, plead to test people.” #COVID19 

CVS says its 10,000 pharmacies alone can do 1M #covid19  shots per day once fully activated:

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"We are terrible at assessing risk," vaccines expert @DrPaulOffit  tells reporters in briefing. "People ask me what's the most dangerous aspect of getting vaccines - the most dangerous aspect is driving to the location to get the vaccine."

Fauci: I’m not entirely sure what president was referring to, but believe it was a report of hydroxychloroquine and azythromicin. Many of the things you hear out there are anecdotal reports. They may be true - but the only way to know is randomized trials #COVID19 

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