Meg Tirrell

Meg Tirrell


Biotech and pharma reporter for @CNBC

94382 followers  •  3584 follow  •    •   https://t.co/OPub4UDJuD

(And of course Pfizer's dose for age 5-11 is 1/3 the adult dose.)

Note Moderna is still waiting on FDA decision on EUA for 12-17 year olds, which it submitted June 10

J&J'ers, your day for data has arrived. Co out with a ton of new information (press released) on its #covid19  vaccine: -2 shots given 2 months apart = 94% efficacy against moderate-severe/critical Covid in US; 75% globally -booster to 1 dose at 6 months = 9-12x antibodies (1/)

-J&J cites real-world study of 1-shot #covid19  vaccine that suggests "no evidence of reduced effectiveness over the study duration, including when the Delta variant became dominant in the U.S. " (conducted March-late July 2021): 81% VE for hospitalization; 79% for infections (2/)

-J&J also updates on phase 3 1-shot #covid19  vaccine results, noting "somewhat lower vaccine efficacy against severe/critical disease caused by variants " - 93% against reference strain, 72% overall. J&J says analysis included countries with high lambda & gamma in circulation (3/)

Here is J&J's press release with all of this information. May I just note, holy confidence intervals. This one was a doozy. (4/4)

Pfizer CEO @AlbertBourla  joins us next on @SquawkCNBC  to discuss new agreement w US govt to supply 500M #covid19  vaccine doses for donation globally, plus boosters, vaccines for kids - tune in

Gilead out w new results on remdesivir for just diagnosed #covid19  patients not in hospital, but at high risk of progression: Says 3 days of IV treatment reduced risk of hospitalization by 87% by day 28 vs placebo Appears similar to monoclonal antibodies, but 3 days of IV?

2-day CDC Advisory Committee on Immunization Practices meeting kicking off now. Today they'll discuss considerations around boosters as well as updated information about #covid19  vaccines in pregnancy; tomorrow will include a vote on Pfizer booster.

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Pfizer puts out statement in response to numerous states saying they’ve been told their allotments of #covid19  vaccine have been reduced, & as FL cited Pfizer production issues as reason - noting no issues and millions of doses in warehouse they haven’t received instructions for.

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Dr Fauci: "There is a fact that permeates virology, and that is: Viruses cannot mutate if they don't replicate." Put it on a?

Quest Diagnostics says its average turnaround time for #COVID19  tests is now 7 or more days for non priority 1 patients

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Pfizer CFO on timeline for #covid19  vaccine for kids, today at Morgan Stanley conf: -results in kids 5-11 by end of Sept, filing for EUA early Oct -filing for EUA for kids 6 months - 5 years about a month later, early Nov (clarity on timeline for younger kids is new) (1/2)

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Weill Cornell’s Dr Matt McCarthy: “At one of the busiest hospitals in the country, I don’t have (a test) at my fingertips. I still have to call the Dept of Health, make my case, plead to test people.” #COVID19 

Regeneron notes of report President Trump has antibodies: “Given the volume of IgG antibodies delivered in our therapy, and the timing of these tests, it is likely that the second test is detecting REGN-COV2 antibodies.”

Fauci: I’m not entirely sure what president was referring to, but believe it was a report of hydroxychloroquine and azythromicin. Many of the things you hear out there are anecdotal reports. They may be true - but the only way to know is randomized trials #COVID19 

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